• <xmp id="gswu8"><nav id="gswu8"></nav>
  • <nav id="gswu8"><strong id="gswu8"></strong></nav><nav id="gswu8"></nav>
    Home >  Chemical Encyclopedia > Dimethyl 1,4-cyclohexanedicarboxylate
    Dimethyl 1,4-cyclohexanedicarboxylate
    CAS No.: 94-60-0 Formula: C10H16O4 Molecular Weight: 200.23200
    Search Suppliers

    Dimethyl 1,4-cyclohexanedicarboxylate

    CAS No.: 94-60-0 Formula: C10H16O4 Molecular Weight: 200.23200
    Suppliers: All (107) China Suppliers (66) Price Available (23) Contractor (2)

    Description

    1,4-Cyclohexanedicarboxylic Dimethyl Ester is a building block that has been used as a reactant for the preparation of cycloalkylamide derivatives as inhibitors of the soluble epoxide hydrolase.

    Basic Info

    Chemical Name Dimethyl 1,4-cyclohexanedicarboxylate
    Synonyms

    Dimethyl cyclohexane-1,4-dicarboxylate;

    CAS No. 94-60-0
    Molecular Formula C10H16O4
    Molecular Weight 200.23200
    PSA 52.60000
    LogP 1.13880

    Numbering system

    MDL number MFCD00001460

    Properties

    Appearance & Physical State after melting, clear colorless
    Density 1.1069
    Boiling Point 131-133oC (11 mmHg)
    Melting Point 24-27oC
    Flash Point 94oC
    Refractive Index 1.456-1.46
    Stability Stable under normal temperatures and pressures.
    Storage Condition Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.

    Safety Info

    Safety Statements S37-S61
    HS Code 2917209090
    WGK Germany 1
    Risk Statements R38; R52/53
    Hazard Codes Xi
    SDS 1.0 Expand

    SDS 1.0

    Collapse
    Download/Modify | Technical supported by XiXisys.com. For US version, EU version (23 languages) and more, please refer to xixisys.com/en/sds/search

    SAFETY DATA SHEETS

    According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

    Version: 1.0

    Creation Date: Aug 12, 2017

    Revision Date: Aug 12, 2017

    1.Identification

    1.1 GHS Product identifier

    Product name Dimethyl 1,4-cyclohexanedicarboxylate

    1.2 Other means of identification

    Product number -
    Other names Dimethyl cyclohexane-1,4-dicarboxylate

    1.3 Recommended use of the chemical and restrictions on use

    Identified uses For industry use only. Intermediates
    Uses advised against no data available

    1.4 Supplier's details

    Company MOLBASE (Shanghai) Biotechnology Co., Ltd.
    Address Floor 4 & 5, Building 12, No. 1001 North Qinzhou Road,
    Xuhui District, Shanghai, China
    Telephone +86(21)64956998
    Fax +86(21)54365166

    1.5 Emergency phone number

    Emergency phone number +86-400-6021-666
    Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

    2.Hazard identification

    2.1 Classification of the substance or mixture

    Eye irritation, Category 2

    Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 3

    2.2 GHS label elements, including precautionary statements

    Pictogram(s)
    Signal word

    Warning

    Hazard statement(s)

    H319 Causes serious eye irritation

    Precautionary statement(s)
    Prevention

    P264 Wash ... thoroughly after handling.

    P280 Wear protective gloves/protective clothing/eye protection/face protection.

    P273 Avoid release to the environment.

    Response

    P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.

    P337+P313 If eye irritation persists: Get medical advice/attention.

    Storage

    none

    Disposal

    P501 Dispose of contents/container to ...

    2.3 Other hazards which do not result in classification

    none

    3.Composition/information on ingredients

    3.1 Substances

    Chemical name Common names and synonyms CAS number EC number Concentration
    Dimethyl 1,4-cyclohexanedicarboxylate Dimethyl 1,4-cyclohexanedicarboxylate 94-60-0 none 100%

    4.First-aid measures

    4.1 Description of necessary first-aid measures

    General advice

    Consult a physician. Show this safety data sheet to the doctor in attendance.

    If inhaled

    If breathed in, move person into fresh air. If not breathing, give artificial respiration. Consult a physician.

    In case of skin contact

    Wash off with soap and plenty of water. Consult a physician.

    In case of eye contact

    Rinse thoroughly with plenty of water for at least 15 minutes and consult a physician.

    If swallowed

    Never give anything by mouth to an unconscious person. Rinse mouth with water. Consult a physician.

    4.2 Most important symptoms/effects, acute and delayed

    no data available

    4.3 Indication of immediate medical attention and special treatment needed, if necessary

    /SRP:/ Immediate first aid: Ensure that adequate decontamination has been carried out. If patient is not breathing, start artificial respiration, preferably with a demand valve resuscitator, bag-valve-mask device, or pocket mask, as trained. Perform CPR if necessary. Immediately flush contaminated eyes with gently flowing water. Do not induce vomiting. If vomiting occurs, lean patient forward or place on the left side (head-down position, if possible) to maintain an open airway and prevent aspiration. Keep patient quiet and maintain normal body temperature. Obtain medical attention. /Poisons A and B/

    5.Fire-fighting measures

    5.1 Extinguishing media

    Suitable extinguishing media

    Use water spray, alcohol-resistant foam, dry chemical or carbon dioxide.

    5.2 Specific hazards arising from the chemical

    no data available

    5.3 Special protective actions for fire-fighters

    Wear self-contained breathing apparatus for firefighting if necessary.

    6.Accidental release measures

    6.1 Personal precautions, protective equipment and emergency procedures

    Use personal protective equipment. Avoid dust formation. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Evacuate personnel to safe areas. Avoid breathing dust. For personal protection see section 8.

    6.2 Environmental precautions

    Prevent further leakage or spillage if safe to do so. Do not let product enter drains. Discharge into the environment must be avoided.

    6.3 Methods and materials for containment and cleaning up

    Pick up and arrange disposal. Sweep up and shovel. Keep in suitable, closed containers for disposal.

    7.Handling and storage

    7.1 Precautions for safe handling

    Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Avoid exposure - obtain special instructions before use.Provide appropriate exhaust ventilation at places where dust is formed. For precautions see section 2.2.

    7.2 Conditions for safe storage, including any incompatibilities

    Store in cool place. Keep container tightly closed in a dry and well-ventilated place.

    8.Exposure controls/personal protection

    8.1 Control parameters

    Occupational Exposure limit values

    no data available

    Biological limit values

    no data available

    8.2 Appropriate engineering controls

    Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday.

    8.3 Individual protection measures, such as personal protective equipment (PPE)

    Eye/face protection

    Safety glasses with side-shields conforming to EN166. Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

    Skin protection

    Wear impervious clothing. The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace. Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique(without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it.

    Respiratory protection

    Wear dust mask when handling large quantities.

    Thermal hazards

    no data available

    9.Physical and chemical properties

    Physical state after melting, clear colorless
    Colour Partially crystalline solid
    Odour no data available
    Melting point/ freezing point 209°C(lit.)
    Boiling point or initial boiling point and boiling range 195°C/12mmHg(lit.)
    Flammability no data available
    Lower and upper explosion limit / flammability limit no data available
    Flash point 109°C(lit.)
    Auto-ignition temperature no data available
    Decomposition temperature no data available
    pH no data available
    Kinematic viscosity 8 cP at 20°C, 3.9 cP at 31.5°C, 3.3 cP 44°C, 2.2 cP at 60°C
    Solubility In water, 12,000 mg/L at 25°C
    Partition coefficient n-octanol/water (log value) log Kow = 2.11 (est)
    Vapour pressure 0.00441 mm Hg at 25°C /Extrapolated from data at higher temperatures/
    Density and/or relative density 1.1069
    Relative vapour density 6.91 (Air = 1)
    Particle characteristics no data available

    10.Stability and reactivity

    10.1 Reactivity

    no data available

    10.2 Chemical stability

    Stable under recommended storage conditions.

    10.3 Possibility of hazardous reactions

    no data available

    10.4 Conditions to avoid

    no data available

    10.5 Incompatible materials

    no data available

    10.6 Hazardous decomposition products

    no data available

    11.Toxicological information

    Acute toxicity

    • Oral: LD50 Rats (male) oral >5000 mg/kg
    • Inhalation: no data available
    • Dermal: no data available

    Skin corrosion/irritation

    no data available

    Serious eye damage/irritation

    no data available

    Respiratory or skin sensitization

    no data available

    Germ cell mutagenicity

    no data available

    Carcinogenicity

    no data available

    Reproductive toxicity

    no data available

    STOT-single exposure

    no data available

    STOT-repeated exposure

    no data available

    Aspiration hazard

    no data available

    12.Ecological information

    12.1 Toxicity

    • Toxicity to fish: LC50; Species: Pimephales promelas (Fathead minnow); Conditions: freshwater, static, 23-25°C, pH 7.7-8, alkalinity 50 mg/L CaCO3, dissolved oxyen 6.0-5.4 mg/L; Concentration: 23 mg/L for 96 hr /purity 99.9%
    • Toxicity to daphnia and other aquatic invertebrates: LC50; Species: Daphnia magna (Water flea); Conditions: freshwater, static, 23-25°C, pH 7.7-7.9, alkalinity 44 mg/L CaCO3, hardness 82 mg/L CaCO3, dissolved oxygen 8.0-8.1 mg/L; Concentration: >100 mg/L for 96 hr /purity 99.9%
    • Toxicity to algae: no data available
    • Toxicity to microorganisms: no data available

    12.2 Persistence and degradability

    AEROBIC: Using OECD Guide-line 302B (Inherent biodegradability: Modified Zahn-Wellens Test) and a non-adapted activated sludge inoculum, dimethyl hexahydroterephthalate reached 98% after 14-days(1). Dimethyl hexahydroterephthalate, present at 52.3 mg/L, reached 82% of its theoretical BOD in 4 weeks using a non-adapted activated sludge inoculum(1). Using OECD Guide-line 301B (Ready biodegradation using the CO2 evolution test, Modified Sturm), dimethyl hexahydroterephthalate reached 81% and 79% degradation at 10 mg/L and 20 mg/L concentrations, respectively, over a 35-day incubation period(2); time for 10% degradation was 11 days(2).

    12.3 Bioaccumulative potential

    An estimated BCF of 11 was calculated in fish for dimethyl hexahydroterephthalate(SRC), using an estimated log Kow of 2.11(1) and a regression-derived equation(1). According to a classification scheme(2), this BCF suggests the potential for bioconcentration in aquatic organisms is low(SRC).

    12.4 Mobility in soil

    Using a structure estimation method based on molecular connectivity indices(1), the Koc of dimethyl hexahydroterephthalate can be estimated to be 31(SRC). According to a classification scheme(2), this estimated Koc value suggests that dimethyl hexahydroterephthalate is expected to have very high mobility in soil.

    12.5 Other adverse effects

    no data available

    13.Disposal considerations

    13.1 Disposal methods

    Product

    The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.

    Contaminated packaging

    Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.

    14.Transport information

    14.1 UN Number

    ADR/RID: UN2925 IMDG: UN2925 IATA: UN2925

    14.2 UN Proper Shipping Name

    ADR/RID: FLAMMABLE SOLID, CORROSIVE, ORGANIC, N.O.S.
    IMDG: FLAMMABLE SOLID, CORROSIVE, ORGANIC, N.O.S.
    IATA: FLAMMABLE SOLID, CORROSIVE, ORGANIC, N.O.S.

    14.3 Transport hazard class(es)

    ADR/RID: 4.1 IMDG: 4.1 IATA: 4.1

    14.4 Packing group, if applicable

    ADR/RID: II IMDG: II IATA: II

    14.5 Environmental hazards

    ADR/RID: no IMDG: no IATA: no

    14.6 Special precautions for user

    no data available

    14.7 Transport in bulk according to Annex II of MARPOL 73/78 and the IBC Code

    no data available

    15.Regulatory information

    15.1 Safety, health and environmental regulations specific for the product in question

    Chemical name Common names and synonyms CAS number EC number
    Dimethyl 1,4-cyclohexanedicarboxylate Dimethyl 1,4-cyclohexanedicarboxylate 94-60-0 none
    European Inventory of Existing Commercial Chemical Substances (EINECS) Listed.
    EC Inventory Listed.
    United States Toxic Substances Control Act (TSCA) Inventory Listed.
    China Catalog of Hazardous chemicals 2015 Not Listed.
    New Zealand Inventory of Chemicals (NZIoC) Not Listed.
    Philippines Inventory of Chemicals and Chemical Substances (PICCS) Listed.
    Vietnam National Chemical Inventory Not Listed.
    Chinese Chemical Inventory of Existing Chemical Substances (China IECSC) Listed.

    16.Other information

    Information on revision

    Creation Date Aug 12, 2017
    Revision Date Aug 12, 2017

    Abbreviations and acronyms

    • CAS: Chemical Abstracts Service
    • ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
    • RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
    • IMDG: International Maritime Dangerous Goods
    • IATA: International Air Transportation Association
    • TWA: Time Weighted Average
    • STEL: Short term exposure limit
    • LC50: Lethal Concentration 50%
    • LD50: Lethal Dose 50%
    • EC50: Effective Concentration 50%

    References

    • IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
    • HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
    • IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
    • eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
    • CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
    • ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
    • ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
    • Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
    • ECHA - European Chemicals Agency, website: https://echa.europa.eu/

    Disclaimer: The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. We as supplier shall not be held liable for any damage resulting from handling or from contact with the above product.
    MSDS Expand
    1H NMR : PredictExpand

    NMR Spectrum 1H NMR : Predict

    Collapse
    IR : liquid filmExpand
    Mass Expand
    Recommended Suppliers
    More Suppliers>>
    Other items you might be interested in
    Category in MOLBASE
    天天干夜夜操