• <xmp id="gswu8"><nav id="gswu8"></nav>
  • <nav id="gswu8"><strong id="gswu8"></strong></nav><nav id="gswu8"></nav>
    N-methylaniline
    CAS No.: 100-61-8 Formula: C7H9N Molecular Weight: 107.15300
    Search Suppliers

    N-methylaniline

    CAS No.: 100-61-8 Formula: C7H9N Molecular Weight: 107.15300
    Suppliers: All (65) China Suppliers (64) Price Available (10) Contractor (11)

    Description

    N-Methylaniline is an aniline derivative. It is an organic compound with the chemical formula C6H5NH(CH3). The substance exists as a colorless or slightly yellow viscous liquid and turns brown when exposed to air. The chemical is insoluble in water. It is used as a latent and coupling solvent and is also used as an intermediate for dyes, agrochemicals and other organic products manufacturing. N-Methylaniline is a principal component of MMA (monomethylaniline), an antiknock agent, used to increase the octane number, more effective than Methyl tert-butyl ether. Usually added to gasoline in concentrations around 1.3% mass.

    Numbering system

    RTECS number BY4550000
    MDL number MFCD00008283
    EINECS number 202-870-9

    Properties

    Appearance & Physical State pale yellow to brown liquid
    Density 0.987
    Boiling Point 195oC
    Melting Point -57oC
    Flash Point 86oC
    Refractive Index 1.5694-1.5714
    Water Solubility 30 g/L
    Stability Stability Combustible. Incompatible with strong oxidizing agents. Discolours upon exposure to air.
    Storage Condition Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
    Vapor Pressure 0.325mmHg at 25°C

    Safety Info

    RTECS BY4550000
    Hazard Class 6.1
    Safety Statements S28-S36/37-S45-S60-S61
    HS Code 2921420090
    WGK Germany 3
    Packing Group III
    RIDADR UN 2294
    Risk Statements R23/24/25; R33; R50/53
    Hazard Codes T
    SDS 1.0 Expand

    SDS 1.0

    Collapse
    Download/Modify | Technical supported by XiXisys.com. For US version, EU version (23 languages) and more, please refer to xixisys.com/en/sds/search

    SAFETY DATA SHEETS

    According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

    Version: 1.0

    Creation Date: Aug 10, 2017

    Revision Date: Aug 10, 2017

    1.Identification

    1.1 GHS Product identifier

    Product name N-methylaniline

    1.2 Other means of identification

    Product number -
    Other names N-methyl-aniline

    1.3 Recommended use of the chemical and restrictions on use

    Identified uses For industry use only.
    Uses advised against no data available

    1.4 Supplier's details

    Company MOLBASE (Shanghai) Biotechnology Co., Ltd.
    Address Floor 4 & 5, Building 12, No. 1001 North Qinzhou Road,
    Xuhui District, Shanghai, China
    Telephone +86(21)64956998
    Fax +86(21)54365166

    1.5 Emergency phone number

    Emergency phone number +86-400-6021-666
    Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

    2.Hazard identification

    2.1 Classification of the substance or mixture

    Acute toxicity - Oral, Category 3

    Acute toxicity - Dermal, Category 3

    Acute toxicity - Inhalation, Category 3

    Specific target organ toxicity – repeated exposure, Category 2

    Hazardous to the aquatic environment, short-term (Acute) - Category Acute 1

    Hazardous to the aquatic environment, long-term (Chronic) - Category Chronic 1

    2.2 GHS label elements, including precautionary statements

    Pictogram(s)
    Signal word

    Danger

    Hazard statement(s)

    H301 Toxic if swallowed

    H311 Toxic in contact with skin

    H331 Toxic if inhaled

    H410 Very toxic to aquatic life with long lasting effects

    Precautionary statement(s)
    Prevention

    P264 Wash ... thoroughly after handling.

    P270 Do not eat, drink or smoke when using this product.

    P280 Wear protective gloves/protective clothing/eye protection/face protection.

    P261 Avoid breathing dust/fume/gas/mist/vapours/spray.

    P271 Use only outdoors or in a well-ventilated area.

    P260 Do not breathe dust/fume/gas/mist/vapours/spray.

    P273 Avoid release to the environment.

    Response

    P301+P310 IF SWALLOWED: Immediately call a POISON CENTER/doctor/…

    P321 Specific treatment (see ... on this label).

    P330 Rinse mouth.

    P302+P352 IF ON SKIN: Wash with plenty of water/...

    P312 Call a POISON CENTER/doctor/…if you feel unwell.

    P361+P364 Take off immediately all contaminated clothing and wash it before reuse.

    P304+P340 IF INHALED: Remove person to fresh air and keep comfortable for breathing.

    P311 Call a POISON CENTER/doctor/…

    P314 Get medical advice/attention if you feel unwell.

    P391 Collect spillage.

    Storage

    P405 Store locked up.

    P403+P233 Store in a well-ventilated place. Keep container tightly closed.

    Disposal

    P501 Dispose of contents/container to ...

    2.3 Other hazards which do not result in classification

    none

    3.Composition/information on ingredients

    3.1 Substances

    Chemical name Common names and synonyms CAS number EC number Concentration
    N-methylaniline N-methylaniline 100-61-8 none 100%

    4.First-aid measures

    4.1 Description of necessary first-aid measures

    General advice

    Consult a physician. Show this safety data sheet to the doctor in attendance.

    If inhaled

    Fresh air, rest. Refer for medical attention.

    In case of skin contact

    Remove contaminated clothes. Rinse and then wash skin with water and soap. Refer for medical attention .

    In case of eye contact

    Rinse with plenty of water for several minutes (remove contact lenses if easily possible).

    If swallowed

    Rinse mouth. Give a slurry of activated charcoal in water to drink. Refer for medical attention .

    4.2 Most important symptoms/effects, acute and delayed

    Inhalation causes dizziness and headache. Ingestion causes blush discoloration (cyanosis) of lips, ear lobes, and fingernail beds. Liquid irritates eyes. Absorption through skin produces same symptoms as for ingestion. (USCG, 1999)

    4.3 Indication of immediate medical attention and special treatment needed, if necessary

    Absorption, Distribution and Excretion

    N-METHYLANILINE IS DISTRIBUTED IN THE LIVER, KIDNEY, LUNG, SMALL INTESTINE, BRAIN, & BLADDER TISSUE.

    5.Fire-fighting measures

    5.1 Extinguishing media

    Suitable extinguishing media

    Excerpt from ERG Guide 153 [Substances - Toxic and/or Corrosive (Combustible)]: SMALL FIRE: Dry chemical, CO2 or water spray. LARGE FIRE: Dry chemical, CO2, alcohol-resistant foam or water spray. Move containers from fire area if you can do it without risk. Dike fire-control water for later disposal; do not scatter the material. FIRE INVOLVING TANKS OR CAR/TRAILER LOADS: Fight fire from maximum distance or use unmanned hose holders or monitor nozzles. Do not get water inside containers. Cool containers with flooding quantities of water until well after fire is out. Withdraw immediately in case of rising sound from venting safety devices or discoloration of tank. ALWAYS stay away from tanks engulfed in fire. (ERG, 2016)

    5.2 Specific hazards arising from the chemical

    Special Hazards of Combustion Products: Toxic vapors are generated when heated. (USCG, 1999)

    5.3 Special protective actions for fire-fighters

    Wear self-contained breathing apparatus for firefighting if necessary.

    6.Accidental release measures

    6.1 Personal precautions, protective equipment and emergency procedures

    Use personal protective equipment. Avoid dust formation. Avoid breathing vapours, mist or gas. Ensure adequate ventilation. Evacuate personnel to safe areas. Avoid breathing dust. For personal protection see section 8.

    6.2 Environmental precautions

    Personal protection: chemical protection suit including self-contained breathing apparatus. Do NOT let this chemical enter the environment. Collect leaking liquid in sealable containers. Absorb remaining liquid in sand or inert absorbent. Then store and dispose of according to local regulations.

    6.3 Methods and materials for containment and cleaning up

    Pick up and arrange disposal. Sweep up and shovel. Keep in suitable, closed containers for disposal.

    7.Handling and storage

    7.1 Precautions for safe handling

    Avoid contact with skin and eyes. Avoid formation of dust and aerosols. Avoid exposure - obtain special instructions before use.Provide appropriate exhaust ventilation at places where dust is formed. For precautions see section 2.2.

    7.2 Conditions for safe storage, including any incompatibilities

    Separated from strong oxidants, strong acids and food and feedstuffs. Keep in a well-ventilated room. Store in an area without drain or sewer access.IN GENERAL, MATERIALS WHICH ARE TOXIC AS STORED OR WHICH CAN DECOMP INTO TOXIC COMPONENTS...SHOULD BE STORED IN A COOL, WELL-VENTILATED PLACE, OUT OF DIRECT RAYS OF THE SUN, AWAY FROM AREAS OF HIGH FIRE HAZARD, & SHOULD BE PERIODICALLY INSPECTED... INCOMPATIBLE MATERIALS SHOULD BE ISOLATED FROM EACH OTHER.

    8.Exposure controls/personal protection

    8.1 Control parameters

    Occupational Exposure limit values

    Recommended Exposure Limit: 10 Hr Time-Weighted Avg: 0.5 ppm (2 mg/cu m), skin.

    Biological limit values

    no data available

    8.2 Appropriate engineering controls

    Handle in accordance with good industrial hygiene and safety practice. Wash hands before breaks and at the end of workday.

    8.3 Individual protection measures, such as personal protective equipment (PPE)

    Eye/face protection

    Safety glasses with side-shields conforming to EN166. Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU).

    Skin protection

    Wear impervious clothing. The type of protective equipment must be selected according to the concentration and amount of the dangerous substance at the specific workplace. Handle with gloves. Gloves must be inspected prior to use. Use proper glove removal technique(without touching glove's outer surface) to avoid skin contact with this product. Dispose of contaminated gloves after use in accordance with applicable laws and good laboratory practices. Wash and dry hands. The selected protective gloves have to satisfy the specifications of EU Directive 89/686/EEC and the standard EN 374 derived from it.

    Respiratory protection

    Wear dust mask when handling large quantities.

    Thermal hazards

    no data available

    9.Physical and chemical properties

    Physical state pale yellow to brown liquid
    Colour COLORLESS OR SLIGHTLY YELLOW LIQ
    Odour Weak, ammonia-like odor.
    Melting point/ freezing point -57°C(lit.)
    Boiling point or initial boiling point and boiling range 196°C(lit.)
    Flammability Class IIIA Combustible Liquid: Fl.P. at or above 60°C and below 93.33°C.Combustible. Gives off irritating or toxic fumes (or gases) in a fire.
    Lower and upper explosion limit / flammability limit no data available
    Flash point 83°C(lit.)
    Auto-ignition temperature no data available
    Decomposition temperature no data available
    pH no data available
    Kinematic viscosity 2.568 cP @ 15°C; 1.766 cP @ 30°C
    Solubility In water:30 g/L
    Partition coefficient n-octanol/water (log value) Log kow = 1.66
    Vapour pressure 0.325mmHg at 25°C
    Density and/or relative density 0.987
    Relative vapour density 3.9 (Relative to Air)
    Particle characteristics no data available

    10.Stability and reactivity

    10.1 Reactivity

    no data available

    10.2 Chemical stability

    ... TURNS REDDISH BROWN ON STANDING.

    10.3 Possibility of hazardous reactions

    N-METHYLANILINE is an aryl an amine. Neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated in combination with strong reducing agents, such as hydrides.

    10.4 Conditions to avoid

    no data available

    10.5 Incompatible materials

    CAN REACT WITH OXIDIZING MATERIALS

    10.6 Hazardous decomposition products

    WHEN HEATED TO DECOMP, IT EMITS HIGHLY TOXIC FUMES OF /NITROGEN OXIDES/.

    11.Toxicological information

    Acute toxicity

    • Oral: no data available
    • Inhalation: no data available
    • Dermal: no data available

    Skin corrosion/irritation

    no data available

    Serious eye damage/irritation

    no data available

    Respiratory or skin sensitization

    no data available

    Germ cell mutagenicity

    no data available

    Carcinogenicity

    no data available

    Reproductive toxicity

    no data available

    STOT-single exposure

    no data available

    STOT-repeated exposure

    no data available

    Aspiration hazard

    no data available

    12.Ecological information

    12.1 Toxicity

    • Toxicity to fish: no data available
    • Toxicity to daphnia and other aquatic invertebrates: no data available
    • Toxicity to algae: no data available
    • Toxicity to microorganisms: no data available

    12.2 Persistence and degradability

    The BOD of N-methylaniline in coarse-filtered Lake Superior harbor water over the course of 20 days was not sufficiently different from controls to calculate a degradation rate(1). Little BOD resulted when N-methylaniline was incubated at 21°C for 20 days in ground water, river water, or Lake Superior Harbor water(1). In a continuous biological treatment simulation test, complete DOC removal was achieved(3). N-Methylaniline (100 ppm) was moderately biodegradable in an activated sludge test with 42% total organic carbon removed(2). The test solution and acclimation procedure employed attempted to simulate industrial wastewater treated at the Fukashiba treatment plant in Japan. Aberrant behavior of N-methylaniline in a semi-continuous activated sludge (SCAS) biodegradation test was found to result from inadequate acclimation of the inoculum(4). It was degraded by Alcalignes sp. and Corynebacterium sp., both isolated from the activated sludge(4).

    12.3 Bioaccumulative potential

    N-Methylaniline was found to have very low bioconcentration in fish using the procedures of the Ministry of International Trade and Industry (MITI) in Japan(1,2). Using its log Kow of 1.66(3), one would estimate a BCF of 11 for N-methylaniline using a recommended regression equation(4). This would indicate that N-methylaniline would not bioconcentrate in aquatic organisms(SRC).

    12.4 Mobility in soil

    Since the pKa of N-methylaniline is 4.848(2), N-methylaniline will be partially ionized at acidic environmental pHs and its adsorption to soil would be expected to be pH-dependent(SRC). The Koc for N-methylaniline predicted from molecular structure is 65(3). According to a suggested classification scheme(5), this estimated Koc suggests that N- methylaniline will be highly mobile in soil(SRC). Batch equilibrium studies used to determine the adsorption isotherms for N-methylaniline to a Podzol (4.85% OC pH 2.8), an Alfisol (1.25% OC, pH 6.7) and a sediment (1.58% OC, pH 7.1) yielded the results (soil, Freundlich adsorption constants (Kf), Freundlich exponent (1/n), Koc): Podzol, 22.29, 0.89, 460; Alfisol, 0.59, 0.78, 47; Sediment, 1.12, 0.77, 71(1). N-Methylaniline will be almost completely ionized at the pH of the Podzol and therefore ionic interactions may be dominant(1,SRC). N-Methylaniline reacts slowly with humates possibly by adding to quinoidal structures in the humic substances(4). Covalent bond formation is inferred by the lack of extractability of the aniline from the humic material as well as reactions with model compounds(4).

    12.5 Other adverse effects

    no data available

    13.Disposal considerations

    13.1 Disposal methods

    Product

    The material can be disposed of by removal to a licensed chemical destruction plant or by controlled incineration with flue gas scrubbing. Do not contaminate water, foodstuffs, feed or seed by storage or disposal. Do not discharge to sewer systems.

    Contaminated packaging

    Containers can be triply rinsed (or equivalent) and offered for recycling or reconditioning. Alternatively, the packaging can be punctured to make it unusable for other purposes and then be disposed of in a sanitary landfill. Controlled incineration with flue gas scrubbing is possible for combustible packaging materials.

    14.Transport information

    14.1 UN Number

    ADR/RID: UN2294 IMDG: UN2294 IATA: UN2294

    14.2 UN Proper Shipping Name

    ADR/RID: N-METHYLANILINE
    IMDG: N-METHYLANILINE
    IATA: N-METHYLANILINE

    14.3 Transport hazard class(es)

    ADR/RID: 6.1 IMDG: 6.1 IATA: 6.1

    14.4 Packing group, if applicable

    ADR/RID: III IMDG: III IATA: III

    14.5 Environmental hazards

    ADR/RID: yes IMDG: yes IATA: yes

    14.6 Special precautions for user

    no data available

    14.7 Transport in bulk according to Annex II of MARPOL 73/78 and the IBC Code

    no data available

    15.Regulatory information

    15.1 Safety, health and environmental regulations specific for the product in question

    Chemical name Common names and synonyms CAS number EC number
    N-methylaniline N-methylaniline 100-61-8 none
    European Inventory of Existing Commercial Chemical Substances (EINECS) Listed.
    EC Inventory Listed.
    United States Toxic Substances Control Act (TSCA) Inventory Listed.
    China Catalog of Hazardous chemicals 2015 Listed.
    New Zealand Inventory of Chemicals (NZIoC) Listed.
    Philippines Inventory of Chemicals and Chemical Substances (PICCS) Listed.
    Vietnam National Chemical Inventory Listed.
    Chinese Chemical Inventory of Existing Chemical Substances (China IECSC) Listed.

    16.Other information

    Information on revision

    Creation Date Aug 10, 2017
    Revision Date Aug 10, 2017

    Abbreviations and acronyms

    • CAS: Chemical Abstracts Service
    • ADR: European Agreement concerning the International Carriage of Dangerous Goods by Road
    • RID: Regulation concerning the International Carriage of Dangerous Goods by Rail
    • IMDG: International Maritime Dangerous Goods
    • IATA: International Air Transportation Association
    • TWA: Time Weighted Average
    • STEL: Short term exposure limit
    • LC50: Lethal Concentration 50%
    • LD50: Lethal Dose 50%
    • EC50: Effective Concentration 50%

    References

    • IPCS - The International Chemical Safety Cards (ICSC), website: http://www.ilo.org/dyn/icsc/showcard.home
    • HSDB - Hazardous Substances Data Bank, website: https://toxnet.nlm.nih.gov/newtoxnet/hsdb.htm
    • IARC - International Agency for Research on Cancer, website: http://www.iarc.fr/
    • eChemPortal - The Global Portal to Information on Chemical Substances by OECD, website: http://www.echemportal.org/echemportal/index?pageID=0&request_locale=en
    • CAMEO Chemicals, website: http://cameochemicals.noaa.gov/search/simple
    • ChemIDplus, website: http://chem.sis.nlm.nih.gov/chemidplus/chemidlite.jsp
    • ERG - Emergency Response Guidebook by U.S. Department of Transportation, website: http://www.phmsa.dot.gov/hazmat/library/erg
    • Germany GESTIS-database on hazard substance, website: http://www.dguv.de/ifa/gestis/gestis-stoffdatenbank/index-2.jsp
    • ECHA - European Chemicals Agency, website: https://echa.europa.eu/

    Disclaimer: The above information is believed to be correct but does not purport to be all inclusive and shall be used only as a guide. The information in this document is based on the present state of our knowledge and is applicable to the product with regard to appropriate safety precautions. It does not represent any guarantee of the properties of the product. We as supplier shall not be held liable for any damage resulting from handling or from contact with the above product.
    MSDS Expand
    1H NMR : 400 MHz in CDCl3Expand

    NMR Spectrum 1H NMR : 400 MHz in CDCl3

    Collapse

    C7 H9 N 0.05 ml : 0.5 ml CDCl3
    N-methylaniline

    Assign. Shift(ppm)
    A 7.164
    B 6.687
    C 6.558
    D 3.6
    E 2.743

    IR : CCl4 solutionExpand
    Mass Expand
    Raman : 4880 A,200 M,liquidExpand
    ESR : OXIDATION WITH PBA IN ETHANOLExpand
    Exposure Route Type of Test Species Observed Dose/Duration Toxic Effects
    Intravenous LDLo - Lowest published lethal dose Mammal - cat 24 mg/kg 1.Behavioral-somnolence (general depressed activity)
    2.Lungs, Thorax, or Respiration-dyspnea
    3.Lungs, Thorax, or Respiration-cyanosis
    Oral LDLo - Lowest published lethal dose Rodent - rabbit 280 mg/kg 1.Behavioral-somnolence (general depressed activity)
    2.Lungs, Thorax, or Respiration-dyspnea
    3.Lungs, Thorax, or Respiration-cyanosis
    Intravenous LDLo - Lowest published lethal dose Rodent - rabbit 24 mg/kg 1.Behavioral-somnolence (general depressed activity)
    2.Lungs, Thorax, or Respiration-dyspnea
    3.Lungs, Thorax, or Respiration-cyanosis
    Recommended Suppliers
    More Suppliers>>
    Other items you might be interested in
    Category in MOLBASE
    天天干夜夜操